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mTOR Complex 1 (mTORC1): mTORC1, sensitive to rapamycin, regulates cell growth by controlling protein synthesis

In light of these findings, it is rational to propose that p53 may participate in cuproptosis in a context-dependent manner, and activation of p53-mediated cuproptosis could be an attractive strategy to eradicate cancer cells

Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia

Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity

Glutamine metabolism and the tumour microenvironment Glutamine metabolism and immunity Glutamine metabolism and T lymphocytes Tumour immune escape is a phenomenon in which neoplastic cells evade recognition and elimination by the immune system through a variety of mechanisms, thus enabling their survival and proliferation within the organism

Inhibition of iNOS reduced HIF-1 accumulation and worsened epithelial damage, emphasizing NOs protective role via this pathway (111113)