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FEBS letters , 581 (14), 2575-2579

Glutathione, or GSH, is a naturally occurring protein that protects every cell, tissue, and organ from toxic free radicals and diseases

For example, the ethanol-inducible CYP2E1, which is located in the centrilobular hepatocytes, effectively catalyzes the centrilobular hepatotoxicity of acetaminophen, carbon tetrachloride, benzene, and nitrosamines