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10.3389/fphar.2022.1031438 18

doi: 10.1203/PDR.0b013e318212c196 123 MomtazmaneshS.Zare-ShahabadiA.RezaeiN

Other Biological Functions of Selenium In addition to the aforementioned biological functions, selenium has been proven to prevent tumor occurrence, reduce cardiovascular disease mortality, prevent and treat diabetes, prevent neurodegenerative diseases, enhance male fertility, and control inflammatory responses [138,139]

According to the results of CheckMate-649 [5], patients with GC who received Nivolumab in combination with chemotherapy had better clinical benefits than those treated with chemotherapy alone, regardless of the PD-L1 Combined Positive Score (CPS)