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GSH metabolism contributes to FA tolerance in DNA-repair deficient cells Finally, we reasoned that the reaction between FA and GSH forming HSMGSH molecules and their metabolization by ADH5 might limit free FA

In preclinical studies, vitamin C monotherapy at millimolar doses exhibits cytotoxic effects on neuroblastoma, glioma, and GBM cells [80,81,82]

Several pro-inflammatory cytokines or chemokines can cause inflammatory cells to be recruited (Thomas et al., 2017)

& Majtan, T

& Kulhari, H.) (Elsevier, 2020)