what organ produces glutathione How Works in the Body: Master Antioxidant Guide How to increase glutathione levels:

It also allows for the direct study of human cells, which can help to address translational concerns

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Sutherland B.A., Rahman R.M.A., Appleton I

In a CLP-induced mouse model of AKI, the E3 ligase MDM2 increased the expression of LMNB1 by promoting the ubiquitinated degradation of p53.LMNB1 may promote mitochondrial damage and ferroptosis in renal tubular epithelial cells and be involved in the development of AKI[22]

Cell 100(1):5770 Grzywa TM, Klicka K, Wlodarski PK (2020) Regulators at every step-how microRNAs drive tumor cell invasiveness and metastasis

And then there's also that age

Hence, formation of thiyl radical from GSH or proteins may enhance the formation of GSNO or protein-based S-nitrosothiols in the presence of NO