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In: Picher M, Boucher RC, editors

2 Factors implicated include the following: Ultraviolet (UV) light UV light can penetrate the epidermis of the skin and is thought to induce reactive oxygen species and promote melanin production (melanogenesis) in the skin

121 Further, this condition would cause cellular and tissue damage, eventually leading to chronic illnesses such as obesity, diabetes, and cancer

Cell viability assay The cytotoxicity of TB m A, TB m A-Glu, TB p A, and TBpA-Glu against human cancer cell lines (HepG2 and HeLa) and normal liver cell line (LO2) was measured by MTT assays as previously described 46