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However, moderate mitochondrial fission maintains mitochondrial function and cellular homeostasis by activating mitophagy to selectively eliminate damaged mitochondrial components ( Mitochondrial fusion is considered the self-protection mode of damaged organelles, which helps maintain the normal function of mitochondria by promoting the production of networked and elongated mitochondria and plays a vital role in maintaining the stability of mtDNA and improving the efficiency of ATP synthesis, thus helping to restore energy supply in cells (Wang M

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Acknowledgements We thank both anonymous reviewers

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