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Adsorption of heavy metal ions Water pollution caused by heavy metal ions is an escalating global concern owing to their non-biodegradable quality and harmful impacts on human health and the environment

Proteins were concentrated to 2 mg/mL before injection

Results from another study indicated that 4-HNE-binding to collagen II could lead to multiple abnormalities of chondrocyte phenotype and function, suggesting it may contribute to interrupting the extracellular matrix (ECM) homeostasis [79]

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doi: 10.1038/s41380-018-0047-z 161 OwenCReesAMParkerG

These signals promote melanoma cell survival, phenotypic plasticity, and invasive behavior while reinforcing intracellular rewiring programs associated with drug tolerance 75 , including modulation of MAPK signaling, activation of YAP/TAZ pathways, and induction of stress-response transcriptional states 77,78,79,80,81,82