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As described earlier, insulin upon binding to its cognate receptor initiates a phosphorylation cascade, which culminates with the phosphorylation and activation of AKT, which in turn phosphorylates AS160 promoting GLUT4-containing storage vesicles (GSVs) trafficking to the cell membrane (Bruss et al., 2005)

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See Supplementary Material for more details ( 4.3 H 2 S measurement The release of hydrogen sulfide was detected by the methylene blue method

Etomoxir decreases the LDL serum concentration and increases the LDL/HDL ratio in rotenone-exposed mice Rotenone treatment resulted in increased serum levels of glucose, and P479L+R mice showed a decrease in serum glucose levels (Fig