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Anticancer activity The effects of methanolic extract of aerial part of plant on human cancer cell lines (including MCF7, an estrogen-dependent breast adenocarcinoma cell line, A549, a non-small cell lung cancer cell line, and HeLa, a cervical cancer cell line) and normal cell lines (including A7R5, a vascular smooth muscle cell line, and 293 T, a human embryonic kidney cell line transformed with SV40largeTantigen) were assessed Inhibitory concentrations for MCF7 (IC50 = 190 ng/mL), HeLa (IC50 = 284 ng/mL), A7R5 (IC50 = 382 ng/mL) and 293 T (IC50 = 317 ng/mL) cells were all much higher than those for A549 (IC50 = 778 ng/mL) which had a much less pronounced impact [63]

Insights into the role of heme in the mechanism of action of antimalarials

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