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[81] reported that the combination of ethanol and trans -resveratrol at moderate concentrations prevents A neurotoxicity in rat brain cultures, and the synergistic effect was likely due to the action of the combination on the protective antioxidant protein peroxiredoxin-2 (Prx2)

Support for this notion is provided by a laboratory study in which fish oil sensitized colon cancer cells to 5-FU, oxaliplatin (Eloxatin), and irinotecan (Granci 2013)

Johns) 747765 (Springer Berlin Heidelberg, 1975)

Inhibition of NADPH supply by 6-aminonicotinamide: effect on glutathione, nitric oxide and superoxide in J774 cells

This approach lets you assess individual response before adding complexity

Although not prebiotics by traditional definition, these substances can exert significant prebiotic-like effects by regulating gut flora, providing rich resources for liver disease management