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But the standard tirzepatide dosing protocol should still be followed for safety

Kumra S, Jacobsen LK, Lenane M, Zahn TP, Wiggs E, Alaghband-Rad J et al (1998)

Others cycle off completely and reassess before deciding whether additional courses are needed

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Sublingual or intranasal administration increases bioavailability to 6080%, allowing lower nominal doses to match the CNS exposure of higher oral doses