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Released fatty acids cannot enter the mitochondria on their own they require L-Carnitine to carry them across the mitochondrial membrane

Diluted pooled samples were loaded on an Illumina MiSeq and sequenced using a 500-cycle MiSeq Reagent Kit v3

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It has been demonstrated that fisetin-induced inhibition of ERK-1/2 phosphorylation triggered by fisetin can significantly suppress the expression of PDHA1, thereby mitigating cellular apoptosis (134)