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indekiler: Hacim Arttrc (Bitkisel Mikrokristal Selloz), Koenzim Q10 Bitkisel Kapsl (Hidroksi Propil Metil Selloz), Stabilizr (Ya Asitlerinin Magnezyum Tuzlar) Kullanm nerisi: Gnde, 2 adet Phytodef Coenzym Q10 kapsl kullanlmas tavsiye edilmektedir

The automatic freeze-drying mode was set (46 C condenser temperature and 100 mT for the vacuum system)

Nonlinear pharmacokinetic properties of mildronate capsules: a randomized, open-label, single- and multiple-dose study in healthy volunteers

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The result finds under the situation that adds levocarnitine, adopts polyoxyethylene stearic acid ester, polyoxyethylene castor oil, polyoxyethylene hydrogenated Oleum Ricini and/or Polyethylene Glycol 15 hydroxy stearic acid esters can make ubiquinone 10 Solubilising effectively.In addition, sensitization possibly occur during owing to polyoxyethylene castor oil, polyoxyethylene hydrogenated Oleum Ricini injection, so this adjuvant only is used for the application of oral liquid.In the drug administration by injection approach, the preferred solubilizing agent of the present invention is polyoxyethylene stearic acid ester class, Polyethylene Glycol 15 hydroxy stearic acid esters, and these two types of solubilizing agents are to ubiquinone 10 Solubilizing effect better, and add behind the levocarnitine lessly to the stability of formulation influence, the phenomenon that medicine is separated out can not take place in storage period, in addition, also can add phospholipid, poloxamer etc