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Results 3D gels selectively support the survival of a subset of lymphoid tumor cells While growth rates of LCLs (X50-7 and JY) and lymphoma B cells (DG-75 and BL-2) in 2D culture conditions are nearly identical [28], lymphoma B cells form colonies within 3D gels, unlike LCLs (Fig

Collectively, these gaps highlight the need for next-generation tools capable of precise metabolic mapping and for validation in more human-relevant models, such as brain organoids

found that when cells are exposed to an environment of low sugar and other nutrient deficiencies, acetyl-CoA synthase ACSS2 will translocate to the nucleus and catalyze the production of acetyl-CoA from acetic acid, thereby mediating the acetylation of histone H3

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P436 Baxter M

doi:10.1016/B978-0-12-420117-0.00003-7 [PubMed] 32