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Curr Pharm Des 17: 16121632

Although the exact underlying mechanism is not clear, multiple studies have supported the concept of senescences role in renal fibrosis progression through transgenic or pharmacological elimination of senescent cells in animal models [96,97,98]

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A diagnosis of MDD requires five or more of the following symptoms during the same two-week period: Depressed mood most of the day, nearly every day Loss of interest or pleasure in nearly all activities Significant changes in sleep or appetite Fatigue or loss of energy Feelings of worthlessness or excessive guilt Difficulty concentrating or making decisions Thoughts of death or suicide MDD is episodic

Lippai R, Veres-Szkely A, Sziksz E, Iwakura Y, Pap D, Rokonay R, Szebeni B, Lotz G, Bres NJ, Cseh , Szab AJ, Vannay (2021) Immunomodulatory role of Parkinsons disease 7 in inflammatory bowel disease

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