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In conclusion, the metabolism of many amino acids (including Cys, Met, etc.) is involved in the regulation of iron death, which may be a new target for the treatment of iron death-related diseases

Further, the KEGG pathway predicted 81 integrated pathways, among which the top 10 pathways were selected for further analysis

Varying from Mac-CF MDM, Mac-CF AM had no difference in GSH metabolism score, as compared to Ctrl AM

MIF-driven activation of macrophages induces killing of intracellular Trypanosoma cruzi dependent on endogenous production of tumor necrosis factor, nitric oxide and reactive oxygen species