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Hydroquinone lightens the skin by affecting the key enzyme, tyrosinase, for the synthesis of melanin Hydroquinone is a powerful skin lightening ingredient and is regarded as the gold standard treatment for melasma

The second enzyme, glutathione synthase (GS), adds the amino acid glycine to Glyteine to form glutathione

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Advances in proteomics techniques, particularly mass spectrometry combined with affinity enrichment methods such as immobilized metal affinity chromatography and immunoprecipitation, have greatly enhanced the large-scale identification of PTMs in plants [34]

in many of these groups the affected gene has been identified

Prednisolone: Although prednisone has reduced the mineralocorticoid effect, the risk of hypokalemia exists and must be taken into account in particular in the following situations: - when potassium-losing diuretic, laxative or amphotericin B have been given concomitantly or when the patient has vomiting or diarrhea