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Nucleic Acids Res 45 , 22942306 (2017)

doi: 10.1136/ard.2007.070821 198 LiuRSongYLiCZhangZXueZHuangQet al

As previously reported, iron chelators can attenuate symptoms and slow down the progression of AD, which shows the potential for novel therapeutic approaches (Nuez and Chana-Cuevas, 2018)

2013;34(2):139-158.[DOI] 5

Imidazole ketone Erastin (IKE) achieves markedly greater potency and stability through an imidazole ketone scaffold that enables durable target engagement while resisting metabolic clearance (76)