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Two authors independently screened the titles and abstracts, followed by a full-text review of relevant articles to extract key mechanisms and clinical findings discussed in this review

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Moreover, CQCQD offers unique advantages in HTG-AP by modulating key enzyme activity in the glycerophospholipid metabolic pathway

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In the UK, hydroxocobalamin 1 mg intramuscular injection is used: Without neurological involvement : 1 mg three times weekly for two weeks, then maintenance of 1 mg every two to three months With neurological involvement : 1 mg on alternate days until no further improvement in symptoms, then maintenance of 1 mg every two months Lifelong maintenance is required for pernicious anaemia or other irreversible causes of deficiency Oral B12 supplementation may be appropriate for diet-related deficiency in patients without neurological symptoms and with adequate absorption capacity