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In a MASH rat model, 6 weeks of LXR inverse agonist treatment reduced hepatic steatosis and fibrosis (Extended Data Fig

Abbreviations RA: Rheumatoid arthritis HC: Healthy control MS: Mass spectrometry DBS: Dried blood spot PCA: Principal component analysis PLS-DA: Partial least squares discriminant analysis VIP: Variable importance in projection FC: Fold change Ala: Alanine Arg: Arginine Cit: Citrulline Leu: Leucine Lys: Lysine Orn: Ornithine Val: Valine Trp: Tryptophan C0: Free carnitine C2: Acetylcarnitine C3: Propionylcarnitine C4: Butyrylcarnitine C5: Isovalerylcarnitine C8: Octanoylcarnitine C14:1: Tetradecenoylcarnitine C16: Palmitoylcarnitine C16-OH: 3-Hydroxypalmitoylcarnitine C20: Arachidic carnitine RCS: restricted cubic spline SAM: Significance analysis of microarrays RF: Random forest OR: Odd ratios ESR: Erythrocyte sedimentation rate CRP: C-reactive protein MSE: mean square error DBP: diastolic blood pressure References Almutairi, K., Nossent, J., Preen, D., Keen, H

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An outcomes protocol for carpal tunnel release: a comparison of outcomes in patients with and without medical comorbidities