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The extracellular L-cysteine/L-cystine redox balance, and thus the synthesis of GSH, is finely regulated by the intracellular conversion of L-cystine into L-cysteine (10), and its impairment is related to oxidative stress and other pathological disorders

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doi: 10.1038/nrc2223

Specialised survey [30] revealed following characteristic symptoms and signs of the FSP: Low BMI (yes, extremely pronounced) Stress sensitivity (yes, extremely pronounced) Frequently cold extremities (yes, extremely pronounced) Low blood pressure (yes) Dizzy (yes) Pain perception (strong) Prolonged time to fall asleep and shifted circadian rhythms (yes) Perfectionism/meticulous personality (yes, extremely pronounced)

Malins et al