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In order to be taken up by the liver it has to be degraded to amino acids. [I also wonder- since glutamate is elevated in metabolic disease, and a residue in the GSH tripeptide, might it be that providing glycine or serine to support synthesis could be preferred over glutathione

B., Mendoza-Mari Y., Rodriguez-Ulloa A., Garcia-Ojalvo A., et al

For these patients, it is prescribed as a treatment for the reduction of excess abdominal fat and shown to decrease the visceral adipose tissue and waist circumference [2]

Thats despite few clinical studies supporting the effectiveness or safety of these peptides, which are amino acid chains meant to help regulate functions in the body and have become popular among fitness and longevity enthusiasts