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We then established a putative gene signature (comprising gclc , gls , gpx4 , gss , slc25a39 , and e2f1 ) of GSH metabolism (GMGS) in association with therapeutic response

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This schematic highlights how curcumin disrupts key inflammatory cascades such as the IKK/NF-B pathway, shifts immune cell phenotypes toward anti-inflammatory states, suppresses the expression of pro-fibrotic factors such as TGF- and CTGF, and promotes the apoptosis of inflammatory cells

The integration of AI with multi-omics data is essential for advancing the understanding and treatment of Parkinsons disease

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Here we review the evidence for white matter abnormalities in AD with a focus on myelin and oligodendrocytes, the only source of myelination in the central nervous system, and discuss the relationship between white matter changes and the hallmarks of Alzheimers disease