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Individual patient data will be shared in data sets in a deidentified and anonymized format

Patients on this protocol who also use metabolic support agents like Metformin should note that both agents activate AMPK, and physician oversight is warranted to avoid compounding effects on blood glucose that could theoretically cause hypoglycemia in susceptible individuals, though this has not been reported clinically with MOTS-c at standard doses

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However, further, thorough research in this area is required, as caution should be exercised when considering the inclusion of VEGF in potential therapies for neurodegenerative diseases

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