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Global Ischemia-Reperfusion Hearts that underwent 30 minutes of ischemia and reperfusion are presented in Figure 6

doi: 10.1080/08039480701643290, 61

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In the USA, the maximum dosage per day recommended by the manufacturer (MacNeil Consumer Healthcare) was reduced from 4000 mg (eight 500 mg pills) to 3000 mg (six 500 mg pills) in 2011[35]

However, there is no established direct causal link between vitamin B12 and joint pain in the medical literature