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Modulation of -glutamylcysteine synthetase large subunit mRNA expression by butylated hydroxianisole

Inflammatory cytokines adversely affect different components of the central nervous system (CNS) and peripheral nervous system (PNS), which may, in turn, lead to degeneration of neurons and microglial cells, increased BBB permeability, as well as prolonged levels of microglial activation, which impairs neurogenesis (36, 37)

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IV therapy may enhance this process by improving antioxidant levels

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Cuadrado A, Manda G, Hassan A, Alcaraz MJ, Barbas C, Daiber A, Ghezzi P, Len R, Lpez MG, Oliva B, et al