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doi:10.3390/medicina59050985 Chandrakumar H, Khatun N, Gupta T, GrahamHill S, Zhyvotovska A, McFarlane SI

The potential utility of incorporating this mechanism into complex LCR/beta-globin LVs was suggested by our discovery that unwanted RNA splicing is the key determinant of LCR/beta-globin -RV instability and low titers, and that this problem could be largely corrected by the removal of undesirable splice sites [131]

Chang H, Kuo C-F, Yu T-S, Ke L-Y, Hung C-L, Tsai S-Y

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M., French, T

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