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Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population

The placebo effect for those symptoms is unknown, so a randomized placebo-controlled study is needed to confirm those possible improvements

Relevance of LPS translocation has been studied also in heart failure, where it was associated with worsen cachexia state due to pro-inflammatory cytokines secretion [66]

Some researchers put the figure closer to 0.1% or less

For most healthy, supervised patients, side effects are mild and dose related, such as temporary irritation at the injection site

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