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This suppression was notably reversed upon treatment with MHY1485 (Fig

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While the majority of MPO remains in the phagolysosome, up to 30% of total cellular MPO can be secreted into the extracellular surroundings via degranulation, leakage during phagocytosis, or by association with NETs [129]

ILD can be divided into three subcategories: Exposure-related ILD, systemic disease-related ILD, and ILD of unknown cause