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Bioorganic & Medicinal Chemistry 11, 31093114, doi: 10.1016/s0968-0896(03)00242-6 (2003)

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Key points Methotrexate is a key component in the treatment of inflammatory rheumatic diseases and the mainstay of therapy in rheumatoid arthritis

All measured metabolites were significantly altered in autism compared with matched controls in both brain regions analyzed

It is more common in women and individuals with darker skin tones and is often triggered by hormonal changes or sun exposure

Diabetes mellitus is one of the major risk factor for CAD and other risk factors for CAD are hypertension, obesity, smoking and dyslipoproteinemias [2]