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There is a small subset of individuals under the age of 50 who become very ill and die from SARS-CoV-2 infection even in the absence of obvious co-morbidities

Primary Handling Editor: Dimitris Typas, in collaboration with the Nature Structural & Molecular Biology team

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Additionally, the present review focuses on the research progress of the possible mechanisms of action in SIC to provide new ideas for the treatment of SIC in the future

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To validate the in vivo relevance of our cell culture observations, we subsequently examined the effects of HFD on hepatic protein-SSG adduct formation, IKK- glutathionylation, and NF-B activation