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doi: 10.1098/rstb.2016.0527

Redox dysregulation is also linked to protein misfolding by the production of aberrant, non-native disulfide bonds in both mutant SOD1 and TDP-43, which leads to the formation of inclusions and induces toxicity

Ferroptosis Participates In The Pathogenesis Process of PF With an in-depth understanding of the mechanisms of ferroptosis, a growing body of research has revealed that ferroptosis plays a critical role in the pathological process of PF [24, 109]

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