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10.1158/2159-8290.CD-19-0597 58 HuY.LuW.ChenG.WangP.ChenZ.ZhouY.et al (2012)

J.StanleyD

doi: 10.3390/biomedicines9121826

The amine group of lysine can become mono-, di-, or trimethylated by histone methyltransferases (HMTs) [20], and demethylated by histone demethylases (KDM) [21, 22], altering chromatin structure and thus regulating transcription [22]

When preparing a working solution, use an appropriate sterile reconstitution solution or compatible laboratory buffer in accordance with validated laboratory procedures