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Description

Randomized phase III study of lenalidomide versus placebo in RBC transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes and ineligible for or refractory to erythropoiesis-stimulating agents

Liver Regeneration and Inflammation: from Fundamental Science to Clinical Applications

Deficiency of cyclophilin D (CypD), a key player of mPTP opening, partially reduced cisplatin-induced necrosis, indicating an essential role of CypD mediated-mPTP opening for cancer cell demolition after chemotherapy [48]

Cell-intrinsic checkpoint inhibition mechanisms such as PD-1 DNR CAR-T cells and PD-1-disrupted CAR T cells can penetrate into the tumor site [174]

Molecular dynamics (MD) simulation (100 ns) was performed to infer proteinligand stability, and conformational changes were analyzed by free energy landscape (FEL)