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Falutz J, Potvin D, Mamputu JC, et al

Because Sermorelin works by stimulating the pituitary to release its own growth hormone, it was also paired with a diagnostic version ( Geref Diagnostic ) that helped determine whether the pituitary could respond appropriately before treatment was started

Elevated insulin levels following a meal can blunt the GH response

Most cases were mild to moderate

Specifically, pretreatment with the GHSR1a agonist MK-0677 or ghrelin for 30 min resulted in an attenuated response to dopamine, with 60-75% reduction in calcium mobilization