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The modified saRNA also caused less translational inhibition and cell death, improving protein expression both in vitro and in vivo

It is assumed that SNAT activity, which is under of the circadian rhythms control, plays a key role in regulating the rate of MEL synthesis (19, 20)

To become biologically active, it must undergo a tightly regulated, two-step enzymatic conversion process inside the cells

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The actual mechanism is likely to occur via two sequential steps with semiquinone (SQ . ) and superoxide (O2 . ) intermediates