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These data can be promising, but they dont give you a definite answer

Some researchers use sterile saline for certain applications

doi: 10.1111/j.1600-0714.2010.00914.x

The timing of bedtime is deliberate: GH secretion is most active during slow-wave sleep, and dosing sermorelin to coincide with that window is standard clinical practice to achieve the best response from the pituitary