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in preclinical and in-vitro systems it has been studied as a GHRH-receptor agonist on anterior pituitary cells, where it has been observed to stimulate the synthesis and pulsatile release of endogenous growth hormone

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NTP monograph: identifying research needs for assessing safe use of high intakes of folic acid, (2015)

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DOI: 10.1038/s41467-017-01114-1 Therapeutic peptide formulation stability - Review of pH, ionic strength, aggregation, and other formulation variables that affect peptide stability

Protein concentration in the supernatant was determined using the BCA method (Thermo, Pierce), or DC protein assay (Bio-Rad)