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This happens because of how the drug works in the body and is expected

Resistance It is known from a disease called diabetes mellitus, that there can be resistance to the actions of the hormone insulin the main regulator of blood glucose concentrations in many individuals

But maintaining solid B12 status ensures that one easily correctable biological variable isn't quietly undermining your mental health

Natural Sources: Vitamin B12 is primarily found in animal foods such as meat, fish, eggs, and dairy

According to a autoimmune issues (caused by types of anemia) malabsorption (your body cant uptake the vitamin) dietary insufficiency (especially strict vegetarian or vegan diets that dont include fortified grains) A protein called intrinsic factor made in the stomach allows our bodies to absorb vitamin B12