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Reduced absorption of the B12-intrinsic factor complex can be caused by various gastrointestinal conditions including Crohns disease, celiac disease, intestinal bacterial overgrowth and intestinal parasites

This is mainly due to the fact that research has traditionally focused on well-known stress molecules like SA or JA, or simply measured the activity of selected redox enzymes

Heme biosynthesis Heme, an iron-containing tetrapyrrole 22 , can unlock diverse abilities including oxygen binding 23 , electron transport 24 , and enzymatic catalysis

This implicated ROS-induced activation of the JAK2STAT3 pathway

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Kung YA, Chiang HJ, Li ML, Gong YN, Chiu HP, Hung CT, et al