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For instance, studies have shown that chemotherapeutic agents like melphalan can directly disrupt ileal BA reabsorption (156), while other treatments reduce the abundance of key BA-metabolizing bacteria, such as those within the Clostridiales order

H., Jeon, Y

Mitochondria in mammalian cells generate most of the cellular energy by means of the oxidative phosphorylation (OXPHOS) that is essential for myriad cellular functions

Both biomarkers are reliable markers for evaluating oxidative damage in cells, tissues, and biofluids, such as plasma and urine

Role of mitochondrial reactive oxygen species in homeostasis regulation

Finally, dual-targeted CAR approaches do enhance the anticancer efficacy of CAR T cells while minimizing extra tumoral side effects in normal tissues that carry a single antigen