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The SOD activity was detected using the method outlined by Kakkar et al

Carota G, Distefano A, Spampinato M, Giallongo C, Broggi G, Longhitano L, et al

EckburgPBBikEMBernsteinCNPurdomEDethlefsenLSargentMet al

Despite the broad-spectrum anti-cancer properties of the reviewed ESCM constituents, it is noteworthy that certain constituents in Figure 1 (e.g., quercetin, kaempferol, rutin) represent well-documented pan-assay interference compounds (PAINS) (Magkoufopoulou et al., 2011