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HDAC inhibitors can suppress the expression of MMP14 in GBM, and the inhibition of MMP14 helps to reduce tumor angiogenesis, inflammation, cancer cell invasion, and metastasis, thereby promoting tumor radiotherapy resistance

(2011) Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1)

PRMTs can be categorized into three types based on their catalytic activity: Type I PRMTs (PRMT1, PRMT2, PRMT3, PRMT4, PRMT6, and PRMT8), Type II PRMTs (PRMT5 and PRMT9), and Type III PRMTs (PRMT7)

The standard procedure and reagents from the Q5 Site-Directed Mutagenesis kit (NEB) were used to insert mutations, ligate plasmids and transform them into NEB 5 competent cells by heat shock

Additionally, transcription factors p53 and NRF2 also play significant roles in ferroptosis

Mukhtar H, Lee IP, Bend JR (1978) Glutathione S-transferase activities in rat and mouse sperm and human semen