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Perkins, Vicente Gilsanz Magnetic Resonance Imaging.2014

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Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status

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Given the cellular heterogeneity in the tumor microenvironment, and the fact that the contribution of HIF to malignant and stromal cell populations could differentially drive tumor progression, ongoing early clinical trials will help to understand the impact of HIF inhibition and other novel agents targeting the hypoxia pathway in terms of immune control and cancer progression

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