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If the powder does not fully dissolve in the first two to three minutes of swirling, stop and let the vial rest for one to two minutes, then swirl again

One of the fundamental principles of therapeutic drug development is confirmation of end-target engagement, measured most readily and ideally via serum biomarkers

The anti-human p53 (DO-1) antibody was obtained from Santa Cruz Biotechnology (Santa Cruz, CA)

Gene transfer of a human insulin-like growth factor I cDNA enhances tissue engineering of cartilage

Activation of PGC-1 alters the metabolic phenotype through interactions with nuclear respiratory factor and peroxisome proliferator-activated receptor- [Citation8-Citation10], which leads to increased mitochondrial biogenesis and activity

doi: 10.1007/s43032-024-01562-3 33 KurowskaP.MlyczyskaE.DupontJ.RakA