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PMID: 25 ThomsenSF

10.1074/jbc.M310752200 J

Orphan drugs in development for the treatment of friedreichs ataxia: focus on omaveloxolone

Structure 4:11711180

A list of candidate biomarkers was determined from the proteins that presented a Welch t-test q- value less than 0.05 (after BenjaminiHochberg correction for multiple testing) and from the top contributors in component 1 and 2 of a sparse partial least square discriminant analysis (sPLS-Da) computed with the Mixomics R package 56