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Their activation is often observed in the context of neurodegenerative disorders, where they become involved in the clearance of toxic protein aggregates and the promotion of tissue repair

The entire DNA of each isolate was extracted using a bacterial genomic DNA extraction kit (Tiangen Biotech, Beijing, China) following the manufacturers instructions

An exon-skipping mutation in SELENOI was discovered in a patient with hereditary spastic paraplegia, deafness, and blindness, with brain atrophy affecting the cerebellum and midbrain (Horibata et al., 2018)

doi: 10.1038/nrrheum.2014.137 85 ChoudhuryMYinXSchaefbauerKJKangJHRoyBKottomTJet al

The SPOT-synthesis technique: synthetic peptide arrays on membrane supports principles and applications

Prion 5 (3), 150153