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Additionally, behavioral changes in the 6-OHDA mouse model were reversed by the PI3K/Akt signaling pathway (Zhang et al., 2017a), and the reduced number of dopaminergic cells and the levels of dopamine and its metabolites DOPAC and HVA were restored ( Vitamins Vitamins in the body have always been regarded as one of the most bioavailable nutrients

Handy DE, Loscalzo J (2022) The role of glutathione peroxidase-1 in health and disease

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Riederer M, Erwa W, Zimmermann R, Frank S, Zechner R (2009) Adipose tissue as a source of nicotinamide N -methyltransferase and homocysteine

It has been noted that the loss of cell integrity, associated with necrosis is an important hallmark of MPTP and rotenone PD cell models, with elevated expression of RIPK3 (Callizot et al., 2019)

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