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This finding further implicates the mPFC TREK-1 channels linked to mGluR2/3 receptors regulating serotonin neuron activity

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Carnitine plays a critical role in energy production by transporting long-chain fatty acids into the mitochondria, where they undergo beta-oxidation to produce adenosine triphosphate (ATP) [1][3]

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Lipid peroxidation during ferroptosis proceeds as follows: (1) the initial reaction occurs between ROS (e.g., hydroxyl radicals), that seem to be derived from NADPH oxidase rather than mitochondrial ETC, at least under some circumstances (Dixon et al., 2017)